NCF425 Series – Open Frame 425 W medical AC/DC power supply
- Technology
- Open / u-frame power supplies
- Partner
- Advanced Energy
The NCF425 Series is designed for engineers integrating power conversion into critical medical equipment where patient leakage current and isolation require close control. Three standard models provide nominal outputs of 12 V, 24 V or 48 V from a universal 85 to 264 VAC input. The 24 V and 48 V versions deliver up to 425 W with at least 300 LFM airflow, while convection or conduction-cooled operation is available at reduced power. Input-to-output isolation is rated at 4000 VAC with two means of patient protection, complemented by 1500 VAC input-to-ground and output-to-ground isolation. The series also withstands a 5 kV defibrillator pulse and provides patient leakage performance suitable for use in Type CF applications. Integrated remote sense, power-good, inhibit and 5 V standby connections support system-level monitoring and control. Typical integration contexts include atherectomy equipment, electrosurgical systems and other medical devices requiring a compact, low-leakage power stage.

The NCF425 Series is a compact open-frame medical AC/DC power platform for equipment that demands tightly controlled leakage current, reinforced isolation and dependable system integration.
Available in 12 V, 24 V and 48 V single-output versions, the series accepts a universal 85 to 264 VAC input and supports up to 425 W on selected models with at least 300 LFM airflow. For designs that rely on convection or conduction cooling, reduced-power operation is also available.
Integration-focused features include remote sense, power-good, inhibit and a 5 V standby output, while protection functions and medical EMC / safety alignment support use in complex healthcare systems.
Range features
A high level overview of what this range offers
- Universal AC input: 85 to 264 VAC operation supports global mains environments.
- Up to 425 W output: Delivers high power density for medium-power medical systems with forced-air cooling.
- Three standard outputs: Available in 12 V, 24 V and 48 V single-output models.
- Low patient leakage: Input-to-output leakage is below 7 µA in normal conditions, supporting equipment intended for Type CF applications.
- High isolation: 4000 VAC input-to-output isolation provides 2 MOPP, with 1500 VAC input-to-ground and output-to-ground isolation.
- Defibrillator pulse withstand: Designed to tolerate a 5 kV defibrillator pulse.
- Flexible cooling options: 24 V and 48 V models reach 425 W with 300 LFM airflow; reduced-power convection or conduction operation is supported.
- System control features: Includes remote sense, power-good, inhibit and 5 V standby for monitoring and control.
- Comprehensive protection: Overvoltage, overload, short-circuit and thermal protection help safeguard the supply during abnormal conditions.
- Efficient operation: Typical efficiency exceeds 90%, helping reduce internal heat generation.
- Compact mechanical format: 3.5 × 6 × 1.5 inch U-channel design fits space-constrained medical assemblies.
- Long-life design: Electrolytic capacitor life exceeds seven years under the stated operating conditions.
What’s in this range?
All the variants in the range and a comparison of what they offer
| Specification | NCF425 Series |
|---|---|
Conversion type | AC/DC, single output |
Rated output range | 12 V to 48 VDC |
Maximum output power | Up to 425 W with forced-air cooling |
Input voltage | 85 to 264 VAC, single phase |
Input frequency | 47 to 63 Hz |
Input current | 3.7 A maximum at 115 VAC; 1.8 A maximum at 230 VAC |
Inrush current | 40 A maximum, cold start at 264 VAC |
Efficiency | Greater than 90% typical |
No-load input power | Less than 1.0 W |
Input-to-output isolation | 4000 VAC, 2 MOPP |
Input-to-ground isolation | 1500 VAC, 1 MOPP |
Output-to-ground isolation | 1500 VAC, 1 MOPP |
Defibrillator withstand | 5 kV pulse |
Standby output | 5 V standby output included |
Control functions | Remote sense, power-good and inhibit |
MTBF | Greater than 500,000 hours per Telcordia SR-332 Issue 6 at 110 VAC, 25°C and full rated load |
Warranty | 3 years |
Dimensions | 88.9 × 152.4 × 38.1 mm; 3.5 × 6 × 1.5 inches |
Weight | 490 g |
| Specification | NCF425S12K | NCF425S24K | NCF425S48K |
|---|---|---|---|
Nominal output voltage | 12 V | 24 V | 48 V |
Output current with airflow | 30.0 A | 17.5 A | 8.75 A |
Output power with airflow | 365 W | 425 W | 425 W |
Convection or conduction current | 19.58 A | 11.25 A | 5.63 A |
Convection or conduction power | 240 W | 275 W | 275 W |
Required airflow | 300 LFM | 300 LFM | 300 LFM |
| Measurement path | Typical performance | IEC 60601-1 limit |
|---|---|---|
Input to earth | Less than 500 µA normal; less than 1000 µA single-fault | Less than 5 mA normal; less than 10 mA single-fault |
Input to output | Less than 7 µA normal; less than 20 µA single-fault | Less than 10 µA normal; less than 50 µA single-fault |
Output to earth | Less than 45 µA normal | Less than 50 µA normal |
FAQs
for NCF425 Series – Open Frame 425 W medical AC/DC power supply
No. It is a component power supply and cannot itself be declared an applied part or assigned a Type CF classification. It has been evaluated against the relevant isolation, creepage, clearance and patient-leakage requirements for use within equipment intended for Type CF applications, but final compliance remains a system-level responsibility.
The standard models provide 12 V, 24 V or 48 V single outputs. The corresponding model identifiers are NCF425S12K, NCF425S24K and NCF425S48K.
No. The 425 W rating applies to the 24 V and 48 V models with at least 300 LFM airflow. Under convection or conduction cooling, these models are rated at 275 W, while the 12 V model is rated at 240 W.
Input-to-output patient leakage is below 7 µA under normal conditions and below 20 µA under a single-fault condition at 264 VAC and 60 Hz. Output-to-earth patient leakage is below 45 µA under normal conditions.
Input-to-output isolation is rated at 4000 VAC and provides 2 MOPP. Input-to-ground and output-to-ground isolation are each rated at 1500 VAC with 1 MOPP.
The series is designed to withstand a 5 kV defibrillator pulse. Equipment designers must still assess the complete medical system, including wiring, connectors, insulation spacing and applied-part circuitry.
A 14-pin signal connector provides remote sense, power-good, inhibit, return and 5 V standby connections. A logic-high or open inhibit input enables the main output, while logic-low disables it.
An external ferrite core may be required on the output cabling to achieve Class B radiated emissions. Without that external core, the documented configuration meets Class A radiated emissions, so EMC verification should be completed in the final equipment enclosure.
The available output remains at its rated level up to 50°C ambient temperature and then derates linearly to 50% at 70°C. Airflow direction, enclosure restrictions and nearby heat sources should be included in the equipment-level thermal assessment.







